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Impact of Dairy Integration Into Canadian Food Guide on Gut Health

RecruitingNAAges 40 Years - 65 YearsAllLaval University
NCT07257913 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The primary objective is to investigate the impact of milk, fermented milk, and soy beverages, incorporated in a diet reflecting adherence to Canadian food guide recommendations on food choices on gut microbiota in middle-aged adults (45-65 years) with abdominal obesity and slightly deteriorated lipids and/or glucose profile. The study aims to discern whether the integration of soy beverages (control), milk, and fermented milk within the CFG diet contributes to distinct gut outcomes and alterations in gut health. We hypothesized that milk and fermented milk will further promote beneficial changes in gut health parameters including gut microbiota composition, trans-epithelial permeability, and inflammation, relative to soy beverages.

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📋 Eligibility rules (as published)
Inclusion Criteria: * IMC \< 45 * Waist circumference \> 80 cm (Women) or 94 cm (men) Exclusion Criteria: * History of diabetes (types 1 and 2), CVD, enteropathy, immune diseases or bariatric surgery * Cancer (diagnostic and/or treatment) during the last 5 years * Antibiotic consumption during the last 3 months * Active smoking or cannabis consumption * Lactose intolerance or allergy, any allergies to foods given in the intervention phases * Irregular defecation patterns * Pregnancy/lactation * Inability to speak French
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What it tests

  • Milk
  • Fermented milk
  • Soy beverage
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Where

1 site
Institute of Nutrition and Functional Foods (INAF)
Québec, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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