🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Effects of Vagus Nerve Stimulation on Motor Function, Respiratory Muscle Strength, and Quality of Life in Stroke Patients

RecruitingNAAges 18 Years - 70 YearsAllIstanbul University - Cerrahpasa
NCT07259577 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Stroke is one of the leading causes of death and permanent disability worldwide. Loss of upper extremity (UE) function after stroke significantly reduces independence and quality of life. Moreover, weakness in the respiratory muscles negatively affects trunk control and respiratory function, limiting overall functional recovery. In recent years, robot-assisted training (RAT) and non-invasive neuromodulation techniques-particularly transcutaneous auricular vagus nerve stimulation (taVNS)-have emerged as promising approaches to enhance neuroplasticity in stroke rehabilitation. This study aims to investigate the effects of taVNS combined with robot-assisted training on upper extremity motor function, respiratory muscle strength, and quality of life in individuals with stroke. This randomized controlled trial will be conducted in collaboration between Istanbul University-Cerrahpaşa and Ist

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Individuals aged 18-70 years diagnosed with ischemic or hemorrhagic stroke lasting longer than 6 months, * Moderate to severe upper extremity weakness (20-50 out of 66 on the Fugl-Meyer Upper Extremity Motor Assessment Scale), * Ability to communicate and understand (Mini Mental State Examination (MMSE) score ≥ 23), * Upper extremity spasticity of 2 or less on the Modified Ashworth Scale. Exclusion Criteria: * Use of any stimulation device, such as a pacemaker or other neurostimulator, * Presence of a medical or cognitive condition (personality disorder, anxiety, depression, etc.) that would prevent participants from participating in the study, * Receiving a Botox injection into the affected upper extremity at least 4 weeks prior, * Severe spasticity in the upper extremity (Modified Ashworth Scale ≥3), * Presence of dysphagia or aphasia, * Presence of cardiac problems such as atrial fibrillation, atrial flutter, sick sinus syndrome, or atrioventricular block.
💊

What it tests

  • Robotics Assisted Education + taVNS
  • Robotics Assisted Education + sham
📍

Where

1 site
İstanbul Üniversitesi-Cerrahpaşa Sağlık Bilimleri Fakültesi Büyükçekmece Yerleşkesi
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy