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PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)

Recruitingn/aAges 18 Years - anyFemaleCopenhagen University Hospital, Hvidovre
NCT07263490 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this prospective observational cohort study is to investigate the pathophysiological mechanisms behind and risk of pre-eclampsia in women pregnant after fertility treatment with oocyte donation. The participants are included in of of two cohorts. One includes women pregnant after oocyte donation whereas the other includes women pregnant after IVF treatment with autologous oocytes. Participants will be followed throughout pregnancy with blood samples, blood pressure, clinical controls and ultrasound examinations. Clinical outcomes will be registered post-partum.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age \> 18 years * BMI \< 35 kg/m2 * Normal wet smear within the past three years * Both nulli- and multiparous * Singletons and multiple gestations Exclusion Criteria: * Age \< 18 years * BMI \> 35 kg/m2 * HIV/ hepatitis * Essential hypertension * Chronic kidney disease * Undiagnosed vaginal bleeding * Uterine malformations * Persisting ovarian cysts * Tumors in hypothalamus, pituitary, thyroid, or adrenal glands. * Previous breast cancer * Known BRCA 1 or 2 gene * Unregulated thyroid disease * Cardiovascular disease * Breast feeding * Present or previous chemotherapy/radiation therapy * Present or previous malignant disease * Smoking * Alcohol/drug abuse
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What it tests

  • Not listed
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Where

6 sites
Copenhagen Fertility Center
Copenhagen, Denmark
Trianglen Fertility Clinic
Hellerup, Denmark
Fertility Clinic, Herlev / Gentofte Hospital
Herlev, Denmark
Sellmer Klinik
København S, Denmark
Fertility Clinic, Rigshospitalet
København Ø, Denmark
Aleris Fertility
Søborg, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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