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Real-Time Dynamic Imaging Study of Normal Pharyngolaryngeal Structures During Barium Swallow (GLAM-III)

Recruitingn/aAges 18 Years - 75 YearsAllZhejiang Cancer Hospital
NCT07264322 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The integrity and functional stability of pharyngolaryngeal anatomical structures are critical for airway management, and the dynamic changes of key structures (e.g., pyriform sinus, cricoid cartilage lamina) during swallowing directly relate to the design and clinical safety of laryngeal masks. This observational study aims to investigate the real-time dynamic changes and physiological movement patterns of normal pharyngolaryngeal structures during barium swallow using routine barium meal examination imaging. The findings will provide anatomical and physiological evidence for optimizing laryngeal mask design and improving its anatomical fit with the pharynx and larynx.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Aged 18-75 years; * No history of pharyngolaryngeal surgery, trauma, or congenital malformation; * No swallowing dysfunction, pharyngolaryngeal inflammation, or neurological diseases affecting swallowing; * No recent use of drugs that affect muscle function (e.g., muscle relaxants, anticholinergics); * Barium meal examination confirms unobstructed oropharyngeal-esophageal pathway; * Normal pharyngolaryngeal anatomical structure (confirmed by preliminary imaging review); * Scheduled to undergo routine barium meal examination at Zhejiang Cancer Hospital for clinical diagnosis. Exclusion Criteria: * Presence of diseases that may compress pharyngolaryngeal structures (e.g., goiter, mediastinal mass); * Allergy to barium sulfate or other components of the barium suspension.
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What it tests

  • Not listed
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Where

1 site
Jiangling Wang
Hangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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