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Acute Effects of Transcutaneous Electrical Nerve Stimulation at Acupoints on Nociceptive Transmission

RecruitingNAAges 20 Years - anyAllChina Medical University Hospital
NCT07267052 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn if transcutaneous electrical nerve stimulation (TENS) applied to acupoints can modulate pain transmission and cortical processing in healthy adult volunteers. The main questions it aims to answer are: * Does TENS at Zhongzhu (SJ3) and Hegu (LI4) change pain-related evoked potentials (PREPs)? * Does acupoint electrical stimulation alter nociceptive pathways reflected by PREP waveform modulation? Researchers will compare PREPs recorded before and after TENS at the two acupoints to see if TENS produces measurable effects on cortical nociceptive responses. Participants will receive low-frequency TENS applied to Zhongzhu (SJ3) and Hegu (LI4), and undergo PREP assessments before and after the intervention to measure cortical responses to standardized noxious stimuli.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Healthy Adult * 20 years or older * The absence of chronic medical conditions * No history of drug allergies * No skin disorders * No current use of medications that could affect study outcomes * Participants maintain a regular daily routine * No history of substance or medication abuse Exclusion Criteria: * History of malignant tumors * History of hand disorders * Has implanted cardiac pacemakers * Pregnancy * Epilepsy * Any other condition that may interfere with the study procedures
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What it tests

  • transcutaneous electrical nerve stimulation (TENS)
  • EEG machine
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Where

1 site
Department of Physical Therapy of China Medical University
Taichung, Taiwan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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