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Thyroid-Stimulating Hormone Levels in Pregnancy and Their Association With Depression, Anxiety, and Sexual Function

Recruitingn/aAges 18 Years - 45 YearsFemaleGaziosmanpasa Research and Education Hospital
NCT07272213 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective, single-center, observational cross-sectional study aims to evaluate the relationship between thyroid-stimulating hormone (TSH) levels and psychological as well as sexual health outcomes during pregnancy. Pregnant individuals will undergo psychometric assessment using the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), the Arizona Sexual Experience Scale (ASEX), and the YKK-13 Quality of Life Scale. The study will investigate whether maternal TSH levels are associated with depression, anxiety, sexual function, and overall quality of life scores. Eligible participants will be pregnant women aged 18-45 years with a singleton pregnancy of at least 6 weeks, who are literate and have provided informed consent. Individuals with a prior psychiatric history, multiple gestation, or existing systemic or endocrine diseases will be excluded. The primary endpoint of t

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📋 Eligibility rules (as published)
Inclusion Criteria: Pregnant women aged 18-45 years Singleton pregnancy Gestational age ≥ 6 weeks Literacy and ability to provide informed consent Availability of a TSH result obtained within the past 4 weeks Cognitive ability sufficient to complete the psychometric questionnaires (Beck Depression Inventory, Beck Anxiety Inventory, ASEX, and YKK-13 Quality of Life Scale) Exclusion Criteria: Multiple pregnancy Previously diagnosed psychiatric disorder or active use of antidepressant/ anxiolytic medication Current treatment for thyroid disease History of thyroid surgery Major systemic illness or significant obstetric complications Age under 18 years or inability to provide informed consent Inability to complete the questionnaires adequately (missing or invalid data) Rationale: Multiple pregnancies are excluded because they differ significantly from singleton pregnancies in terms of hormonal profile, obstetric risks, and psychological stress levels. This exclusion aims to ensure a homogeneous study population.
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What it tests

  • Not listed
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Where

1 site
SBÜ Gaziosmanpaşa Training and Research Hospital
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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