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โ† Trials
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Effect of HIIT on Post-Stroke Fatigue

RecruitingNAAges 40 Years - 80 YearsAllThe Hong Kong Polytechnic University
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In plain words

What the trial is, and whether it could suit you

This study aims to investigate the effect of high-intensity interval training (HIIT) on fatigue severity among individuals with chronic stroke. Participants will be randomly assigned to the HIIT group, the moderate-intensity continuous training (MICT) group, or the stretching group (active control). Each group will participate in supervised exercise sessions three times per week over a 12-week period, totaling 36 sessions. Outcome assessments will be conducted at baseline, mid-intervention (week 6), post-intervention (week 12), and follow-up (week 20). The primary outcome will be fatigue severity. Secondary outcomes will include inflammatory biomarkers and additional health-related indicators.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion criteria: * Age of 40-80 years; * a history of ischemic stroke resulting in unilateral limb impairment 6-60 months prior to consent to participate in the pilot trial; * a stable medical condition; * a subjective feeling of fatigue, defined as a period of apparent fatigue, decreased energy, increased need for rest, or fatigue out of proportion to physical activity for at least 2 weeks during the past month; * ability to communicate with the investigators and lack of significant cognitive deficits; * able to walk for 10 meters with or without a walking aid. Exclusion criteria: * An FSS score of \< 4 (20); * other neurological conditions; * other musculoskeletal comorbidities that would prevent safe participation in exercises; * a medical diagnosis of significant cardiovascular, pulmonary, or metabolic disease(s); * signs or symptoms indicative of significant cardiovascular, pulmonary, or metabolic disease(s) during the previous 3 months; * severe lower limb spasticity (Ashworth Scale score โ‰ฅ 3); * Botulinum toxin use in the affected lower limb within the past six months; * current or previous use of drugs intended to resolve post-stroke fatigue; * active engagement in other stroke rehabilitation trials.
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What it tests

  • HIIT
  • MICT
  • stretching
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Where

1 site
The Hong Kong Polytechnic University
Kowloon, Hong Kong
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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