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Pain Neuroscience Education and Vagus Nerve Stimulation on Recovery in Individuals With Rheumatoid Arthritis

RecruitingNAAges 20 Years - 65 YearsAllMedipol University
NCT07274124 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In the context of this randomized controlled study, patients who are diagnosed with Rheumatoid arthritis in Cerrahpaşa Faculty of Medicine Hospital, will be taken into a rehabilitation program by a qualified physiotherapist to improve their pain, pain perception, inflammatory markers and quality of life, with one of the pain neuroscience education, vagal nerve stimulation and traditional exercise interventions. The results of each intervention method will be analyzed and compared at the end of the 8 weeks study protocol.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Individuals who were diagnosed with RA at least one year ago, * More than score 2.6 in DAS28, * Ages of 20 and 65, * Have been experiencing pain for three months or more, * Score 24 or higher on the Mini Mental State Examination (MMSE), and can follow instructions will be included in the study. Exclusion Criteria: * Individuals under 20 years of age, * Reporting acute pain or pain from injury, * Having a history of surgery within the last year, * Remission in DAS28, * Patients whose medication was changed, * Having a score of \<24 on the MMSE, * Having any of the cerebrovascular disease, cardiovascular disease, symptomatic coronary artery disease, myocardial infarction, congestive heart failure, or uncontrolled hyper/hypotension, * History of vagotomy surgery, or having an implanted electrical/neurostimulator device will not be included in the study.
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What it tests

  • Pain Neuroscience Education
  • Vagal Nerve Stimulation
  • Structured Exercises
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Where

1 site
Cerrahpaşa Faculty of Medicine Hospital
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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