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Combined Effects of INF and OEP in Patients With Diabetic Peripheral Neuropathy

RecruitingNAAges 50 Years - 75 YearsAllRiphah International University
NCT07274735 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

DPN often leads to balance issues, sensory deficits, and chronic pain, which can severely impact daily functioning and independence. INF therapy aims to improve nerve blood flow and alleviate neuropathic symptoms through manual techniques, while the Otago Exercise Program focuses on enhancing strength and balance to reduce fall risk. By comparing these two interventions, this study seeks to identify effective strategies that can improve balance, reduce pain, and enhance the quality of life for individuals suffering from DPN

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 50-75years * Both male and female patients will be included in the study * Patient with type 2 diabetes mellitus (diagnosed by the physician) * Patients with a score ≥ 4 on DN4 scale * Patients have a score on the Timed Up-and-Go (TUG) test of less than 15 s * Able to walk at least 10 meters long Exclusion Criteria: * Patient with presence of any other systemic disease rather than diabetes such as end-stage renal failure, uncontrolled hypertension, severe dyslipidemia, chronic liver disease, autoimmune disease, advanced chronic obstructive pulmonary disease etc * Patients with documented active alcohol or drug misuse * Patient with total or partial amputation of lower extremities * Participants will be also excluded if they were morbidly obese or if pregnant (self-reported) * Patient with active inflammations or other inflammatory neuropathies including chronic inflammatory demyelinating polyneuropathy, proximal diabetic neuropathy, chemotherapy-induced peripheral neuropathy, autonomic neuropathies, or other neuropathies not associated with DM such as B12 deficiency
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What it tests

  • Intraneural facilitation therapy
  • Otago exercise program
  • Intraneural facilitation therapy with Otago exercise program
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Where

1 site
Rasheed Hospital
Lahore, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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