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Physical and Psychosocial Parameters in Takayasu Arteritis and Behçet's Disease: A Comparative Study With Healthy Controls

Recruitingn/aAges 18 Years - anyAllÖZLEM NUR TOK YAMAN
NCT07276087 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Systemic vasculitis refers to a group of rare diseases characterized by inflammation of blood vessel walls, which may cause ischemia and structural damage in various organs. Among large-vessel vasculitides, Takayasu arteritis primarily affects the aorta and its main branches, whereas Behçet's disease is a variable vessel vasculitis involving arteries and veins of all sizes. Both conditions can lead to multisystemic involvement and significantly impact physical and psychosocial health. This observational, case-control study aims to compare multiple physical and psychosocial parameters among individuals with Takayasu arteritis, Behçet's disease, and healthy controls. Assessments will include respiratory and peripheral muscle strength, functional status, exercise capacity, body composition, quality of life, illness perception, and psychological well-being. Measurements will be conducted us

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📋 Eligibility rules (as published)
Inclusion Criteria: Inclusion Criteria (Takayasu Arteritis Group): * Age 18 years or older. * Diagnosis of Takayasu arteritis according to the American College of Rheumatology (ACR) classification criteria. * Voluntary participation with written informed consent. Inclusion Criteria (Behçet's Disease Group): * Age 18 years or older. * Diagnosis of Behçet's disease according to the International Study Group for Behçet's Disease criteria. * Voluntary participation with written informed consent. Inclusion Criteria (Healthy Control Group): * Age 18 years or older. * No history of systemic, rheumatologic, or chronic inflammatory disease. * Voluntary participation with written informed consent. Exclusion Criteria: Exclusion Criteria (Patient Groups - Takayasu Arteritis and Behçet's Disease): * Pregnancy. * Presence of psychiatric disorder or ongoing psychiatric treatment. * Cognitive impairment that may interfere with participation. * Presence of neurological disease (e.g., hemiplegia, Parkinson's disease, multiple sclerosis, vertigo, epilepsy, etc.). * History of any surgical operation within the past year. * Coexisting rheumatic disease other than Takayasu arteritis or Behçet's disease. Exclusion Criteria (Healthy Control Group): * Pregnancy. * Presence of psychiatric disorder or ongoing psychiatric treatment. * Cognitive impairment that may interfere with participation. * Presence of neurological disease (e.g., hemiplegia, Parkinson's disease, multiple sclerosis, vertigo, epilepsy, etc.). * History of any surgical operation within the past year. * History of rheumatologic or chronic inflammatory disease.
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What it tests

  • No intervention (observational study)
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Where

1 site
Pamukkale University
Denizli, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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