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The Effect of Integrating Pain Neuroscience Education(PNE) With Conventional Physiotherapy on Pain and Functional Disability in Patients With Acute Low Back Pain

RecruitingNAAges 18 Years - anyAllIran University of Medical Sciences
NCT07277517 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Acute low back pain is one of the most common health problems in the world. Most people experience it at least once in their lives, and although many cases improve within a few weeks, a significant number of patients continue to struggle with pain, fear of movement, stress, and reduced daily function. These psychological factors-such as catastrophizing ("my back is damaged"), fear of movement ("if I move, it gets worse"), and avoidance behaviors-can slow recovery and increase the risk of the pain becoming chronic. Pain Neuroscience Education (PNE) is a modern educational approach that teaches patients how pain actually works in the nervous system. Instead of focusing only on muscles and bones, PNE helps people understand how the brain interprets pain, why pain can persist even without serious injury, and how thoughts, emotions, and behaviors can influence the experience of pain. Researc

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 years and older. * A primary complaint of acute low back pain (defined as pain between the bottom of the ribs and the gluteal fold), with or without leg pain. * Pain duration of less than 6 weeks. * Absence of any "red flags" for serious spinal pathology (e.g., tumor, infection, fracture, cauda equina syndrome), as confirmed by an orthopedist or neurologist. Exclusion Criteria: * Low back pain lasting more than 3 months (chronic low back pain). * History of spinal surgery within the past 3 years. * Inability to read or understand Persian. * Diagnosed cognitive impairments. * Unwillingness to continue the treatment or study protocol. * Diagnosed rheumatic, neurological, cardiac, metabolic, or respiratory diseases. * Diagnosis of fibromyalgia, chronic fatigue syndrome, loss of skin sensation, or skin inflammation/swelling in the low back area. * Presence or emergence of any "red flag" condition. * Missing more than 3 consecutive treatment sessions. * Previous participation in Pain Neuroscience Education sessions.
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What it tests

  • routine physiotherapy + traditional patient education
  • pain neuroscience education
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Where

1 site
rehabilitation facility, Iran university of medical science
Tehran, Iran
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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