AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Magnetic Resonance Elastography to Monitor Response to Manual Therapy in Myofascial Pain

RecruitingNAAges 18 Years - anyAllMayo Clinic
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

The purpose of this research is to develop and test new Magnetic Resonance Imaging (MRI) methods that look at how muscles and tissues under the skin (myofascial tissues) move and respond to pressure. The investigators want to see how these tissues differ between healthy people and people with pain or injury, and how they change after hands-on treatment (Tuina therapy). The results will also be compared to a group that receives standard care without Tuina therapy. The main questions this study aims to answer are: 1. Can MR elastography (MRE) show changes in how the fascia and the layers between muscles move and stretch before and after manual therapy? 2. Do changes seen on MRE scans match changes in pain, function, and other symptoms reported by participants? 3. Can MRE measurements before treatment help predict which participants are most likely to improve with manual therapy? In this

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Patient Inclusion Criteria: 1. Adult males or females (age โ‰ฅ 18 years) 2. A history of chronic low back for at least 3 months. (Measured by patient history and physical exam) 3. A palpable taut band or nodule within the skeletal muscle 4. Hypersensitive tender spot within the taut band 5. Recognition of current pain complaint by pressure on the tender nodule/taut band 6. Painful limit to the full stretch range of motion Patient Exclusion Criteria: 1. Pregnancy or breastfeeding 2. Any contraindication to an MRI exam, or severe claustrophobia that would prevent safe completion of the scan 3. Previous therapy in the area to be treated within 3 months 4. Previous severe back injury (including fracture) or surgery 5. Any neurological conditions or active systemic disease (e.g. diabetes, peripheral vascular disease, cancer, rheumatoid arthritis) that impaired sensation/pain perception 6. Severe osteoarthritis 7. Skin injuries in the area to be treated 8. Known or suspected clinically significant lumbar disc or other structural spinal pathology considered to be the primary cause of the participant's symptoms or makes study participation or manual therapy inappropriate. 9. Have a known history of any condition or factor judged by the investigators to preclude participation in the study or which might hinder adherence 10. Inability to provide consent.
๐Ÿ’Š

What it tests

  • Tuina treatment
  • Usual care
๐Ÿ“

Where

2 sites
Mayo Clinic in Rochester
Rochester, United States
Mayo Clinic Rochester
Rochester, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy