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Effect of Fluoride Varnish Formulation on the Management of Dentin Hypersensitivity

RecruitingNAAges 18 Years - 40 YearsAllUniversity of Concepcion, Chile
NCT07286344 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized controlled clinical trial aims to determine whether different fluoride varnish formulations reduce dentin hypersensitivity (DH) in young adults diagnosed with DH. The primary purpose of this study is to evaluate the clinical effectiveness of two commercially available fluoride varnishes. The main questions this study aims to answer are: * Does Clinpro Clear® (aqueous base, 9,500 ppm NaF) lead to a greater reduction in dentin hypersensitivity compared with Duraphat® (rosin/resin base, 22,600 ppm NaF)? * Do these varnish formulations improve oral health-related quality of life and patient satisfaction? Researchers will compare a single application of Duraphat® with a single application of Clinpro Clear® to assess differences in hypersensitivity reduction, quality-of-life outcomes, and patient satisfaction. Participants will: * Receive one application of either Duraphat

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age between 18 and 40 years * Absence of systemic diseases with oral manifestations or requiring medications with antisialagogue effects * Fully dentate (excluding third molars or teeth extracted for orthodontic reasons) * Absence of periodontal disease, or periodontal condition in a stable state * Presence of at least one cervical lesion with a Schiff sensitivity score ≥ 1 * No previous treatment or restorative procedures on the target lesions (including no topical fluoride application within the last 6 months) Exclusion Criteria: * Patients requiring long-term use of NSAIDs or other analgesic/anti-inflammatory medications * Patients with allergy to milk proteins * Patients with allergy to organic resins or pine-derived substances * Pregnant or breastfeeding individuals * Patients with fixed orthodontic appliances in place
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What it tests

  • Aqueous fluoride varnish, 9,500 ppm NaF
  • Resin/rosin-based varnish, 22,600 ppm NaF
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Where

1 site
Clinica de Rehabilitación Avanzada e Implantologia (CRAI)
Concepción, Chile
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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