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Treatment for Benign Prostatic Obstruction: Transperineal Laser Ablation

RecruitingNAAges 40 Years - 85 YearsMaleAzienda Ospedaliero-Universitaria Consorziale Pol…
NCT07289243 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

THIS STUDY IS A RANDOMIZED CLINICAL TRIAL COMPARING TRANSURETHRAL PROSTATE RESECTION (TURP) AND ECHOLASER SORACTELITE-TRANSPERINEAL LASER ABLATION (TPLA) IN PATIENTS WITH LOWER URINARY TRACT SYMPTOMS DUE TO BENIGN PROSTATIC OBSTRUCTION. THE PRIMARY GOAL IS TO SHOW THE NON-INFERIORITY OF TPLA VERSUS TURP BY IPSS-SCORE.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Lower urinary tract symptoms (IPSS \>= 8); * Poor efficacy after at least six months of medical therapy or intolerance to medical treatment for BPH; * Prostate volume: 40ml-80ml; * Ability to give informed consent. Exclusion Criteria: * Previous surgery for benign prostatic hyperplasia; * Indwelling bladder catheter or intermittent bladder catheterization; * Diagnosis of bladder stones; * Recurrent urinary tract infections or intraprostatic abscesses; * Severe detrusor hypocontractility or acontractility; * Hydronefrosis due to urinary retention; * Urethral strictures or diagnosis of neurogenic bladder; * Diagnosis of bladder cancer; * Diagnosis or clinical suspicion of prostate cancer.
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What it tests

  • ECHOLASER-TPLA
  • TURP
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Where

2 sites
UOC Urologia e Trapianti di Rene Policlinico di Bari
Bari, Italy
UOC Urologia e Trapianti di Rene Policlinico di Bari
Bari, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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