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Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis

Recruitingn/aAges 50 Years - 90 YearsAllThe Fourth Affiliated Hospital of Zhejiang Univerโ€ฆ
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In plain words

What the trial is, and whether it could suit you

This study aims to systematically evaluate the therapeutic efficacy of dual-channel endoscopic spinal decompression versus lumbar decompression with fusion for degenerative lumbar spondylolisthesis. Patients undergoing either procedure will undergo detailed preoperative and postoperative follow-up to compare outcomes between the two techniques, specifically assessing postoperative pain relief, neurological improvement, and the incidence of surgical complications.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Aged between 50 and 90 years old with a confirmed diagnosis of degenerative lumbar spondylolisthesis; 2. Clinical symptoms include chronic pain, nerve compression, or motor dysfunction, confirmed by imaging studies (e.g., MRI or CT); 3. No significant improvement after at least 3 months of conservative treatment (e.g., medication, physical therapy), meeting surgical indications; 4. Understand and consent to the relevant procedures of this study, and sign the informed consent form. Exclusion Criteria: 1. Patients exhibiting acute spinal cord compression symptoms or requiring urgent surgical intervention; 2. Patients with a history of spinal surgery or conditions such as spinal deformities, severe osteoporosis, or active infections that may compromise surgical outcomes; 3. Patients with severe comorbidities affecting assessment, such as cardiovascular disease, liver or kidney failure, or uncontrolled diabetes; 4. Patients with psychiatric disorders or cognitive impairments preventing understanding or cooperation with the study process; 5. Patients with allergies to anesthetics or surgical equipment that may increase intraoperative risks.
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What it tests

  • Not listed
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Where

1 site
4th Affiliated Hospital, School of Medicine, Zhejiang University
Yiwu, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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