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โ† Trials
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Long-term Follow-up of the Offspring Born to Mothers With a Solid Organ Transplant, Transplantlines Next Generation

Recruitingn/aAges any - anyAllUniversity Medical Center Groningen
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In plain words

What the trial is, and whether it could suit you

Background Pregnancy after all types of solid organ transplantation (SOT) is possible, although these have higher risk of pregnancy complications for mother and child, such as preeclampsia and preterm birth. Thus, the development of the unborn child seems to be affected by the transplant and its consequences such as the immunosuppressive medication use. Worldwide data regarding follow-up after birth is scarce. The very limited existing data existing only in young children are reassuring. However, the investigators hypothesize that there are health risks for the children. Given the side effects of the immunosuppressive medication on patients and limited knowledge from animal studies, the investigators particularly expect cardiovascular effects such as hypertension and kidney damage. These develop over a long time-period and lead late to symptoms. Aims Aim of this study is to gain more in

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Mother with a KTx, LiTx, PTx (including pancreas islet transplantation), HTx or LuTx before pregnancy (including mothers with multiple transplantation types) * Age โ‰ฅ16 years for offspring born to mother with a KTx or LiTx Exclusion Criteria: * No informed consent * Non Dutch or English speaking
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What it tests

  • Not listed
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Where

1 site
University Medical Center Groningen
Groningen, Netherlands
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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