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Central Venous Catheter Placement With Thoracic Ultrasound and Intracavity ECG Positioning

RecruitingNAAges 18 Years - anyAllYork Teaching Hospitals NHS Foundation Trust
NCT07291869 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this interventional study is to assess the feasibility of two bedside techniques for confirming central venous catheter (CVC) placement and detecting complications: * Intracavity ECG monitoring to confirm internal jugular vein CVC tip position. * Thoracic point-of-care ultrasound (POCUS) to rule out pneumothorax following CVC insertion. Participants who require an internal jugular CVC as part of their routine care and meet all inclusion and no exclusion criteria will be randomised to receive either: * Standard care, or * The intervention, consisting of intracavity ECG guidance and thoracic POCUS. The CVC will be inserted either on the left or right side of the neck. All participants will undergo a post-procedure chest X-ray regardless of study arm, to allow comparison of the intervention methods with standard care.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult (aged ≥ 18 years) * Admitted, or planned for admission, to critical care * Requiring central venous catheter insertion as a part of their usual care * Suitable for both right or left internal jugular vein insertion Exclusion Criteria: * Previously randomised into CVC-TIP * Atrial fibrillation on 12-lead ECG * Cardiovascular instability, defined as * Noradrenaline dose \> 0.5mcg/kg/min * Rapidly escalating doses of vasopressors / inotropes * Difficulty in obtaining thoracic ultrasound images due to either * Weight \> 120kg * Existing pneumothorax (either side) * Subcutaneous emphysema * Wounds / dressing over anterior chest wall * Existing pacemaker * Non-English speaking participants * Death perceived as imminent * Any other reason as determined by treating clinician
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What it tests

  • Intracavity ECG
  • Thoracic point of care ultrasound
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Where

1 site
York and Scarborough Teaching Hospitals NHS Foundation Trust
York, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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