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Comprehensive Assessment of First Trimester Pregnancy Loss

Recruitingn/aAges 18 Years - anyFemaleFundació Institut de Recerca de l'Hospital de la …
NCT07293819 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The FIRST-CARE Study is a prospective research project conducted at Hospital de la Santa Creu i Sant Pau (Barcelona, Spain), aimed at better understanding the causes and consequences of first-trimester pregnancy loss (miscarriage). Miscarriage is a common event that affects about 15% of clinically recognized pregnancies and can have both physical and emotional consequences for women and their partners. However, many questions about its causes remain unanswered, and most women do not receive a clear explanation or personalized support after experiencing a loss. This study will include 225 women who have experienced a miscarriage during the first 14 weeks of pregnancy. Two groups will be studied: those who have had a miscarriage for the first time and those with a history of recurrent pregnancy loss (defined as two or more previous miscarriages). The aim is to investigate a wide range of

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📋 Eligibility rules (as published)
Female participants: Inclusion Criteria: * Women aged 18 years or older. * Diagnosis of missed miscarriage in the first trimester (\<14 weeks of gestation) confirmed by ultrasound. * Presence of an intrauterine pregnancy with fetal demise (clinical pregnancy loss). * Willing and able to provide written informed consent. * Ability to understand and complete study procedures. Exclusion Criteria: * Multiple pregnancy (twins or more). * Ectopic pregnancy. * Molar pregnancy (complete or partial hydatidiform mole). * Ongoing pregnancy with fetal cardiac activity. * Inability or unwillingness to comply with study procedures or follow-up. Male participants: no specific inclusion or exclusion criteria will apply to male partners, since the main inclusion criteria is a clinical pregnancy loss.
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What it tests

  • Not listed
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Where

2 sites
Hospital de la Santa Creu i Sant Pau
Barcelona, Spain
Hospital de la Santa Creu i Sant Pau
Barcelona, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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