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Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Cancer Patients

Recruitingn/aAges 65 Years - anyAllDolunay ARIK
NCT07294040 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This observational clinical study aims to investigate the incidence and risk factors of post-induction hypotension (PIH) in geriatric cancer patients undergoing surgery under general anesthesia. PIH is defined as a drop in mean arterial pressure of ≥30% from baseline or below 65 mmHg within the first 20 minutes after anesthesia induction, prior to surgical stimulation. The primary objective is to determine the frequency of PIH in elderly oncology patients. Secondary objectives include evaluating the association of PIH with age, ASA score, cancer type, oncological treatments (chemotherapy/radiotherapy), comorbidities, medication use, anemia, biochemical parameters, and preoperative perfusion index (PI) and pleth variability index (PVI). Findings from this study are expected to contribute to improved perioperative management and to the development of tailored anesthesia protocols for ger

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults ≥65 years of age Patients with a diagnosis of cancer and scheduled for surgery Ability and willingness to provide written informed consent ASA physical status class II-IV Exclusion Criteria: Patients under 65 years of age Patients without a confirmed oncologic diagnosis Refusal to provide written informed consent Patients undergoing regional anesthesia Patients with tracheostomy or requiring multiple intubation attempts History of peripheral arterial disease Use of vasopressors before the start of surgery Uncontrolled hypertension (blood pressure \>180/110 mmHg) Advanced heart failure (Ejection Fraction \<40%) Severe arrhythmias such as atrial fibrillation or significant ventricular arrhythmias that preclude reliable hemodynamic monitoring
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What it tests

  • Not listed
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Where

1 site
Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital
Ankara, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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