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Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.

RecruitingPhase 2Ages 65 Years - anyAllVrije Universiteit Brussel
NCT07294131 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study investigates a new training method designed to help older adults preserve their muscle strength during hospitalization. When older adults are admitted to the hospital and spend long periods in bed, their muscles can weaken very quickly. This condition is known as hospital-associated disability (HAD), and it can lead to longer hospital stays, reduced independence, and an increased risk of complications or even death. Conventional strength training with heavy weights is often too demanding or unsafe for frail patients, especially just after surgery or illness. As a safer alternative, this study combines light muscle exercises with a medically validated technique called blood flow restriction (BFR), which gently reduces blood flow to the leg to boost the effects of light exercises. To make training more engaging and personalized, the GHOSTLY+ system was developed. This system co

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📋 Eligibility rules (as published)
PATIENTS Inclusion Criteria: * Hospitalized, and expected to remain hospitalized for approximately 14 days * 65+ yrs * Unable to bear weight or transfer independently and at high risk of muscle strength loss due to prolonged immobility Exclusion Criteria: * Contraindications for physical exercise as assessed by the treating physician using the risk assessment tool proposed by Kacin et al. (2015) (can be overruled by the physician) * Contraindications for blood flow restriction as assessed by the treating physician (can be overruled by the physician) * Cognitive impairment (MMSE score \< 19) * Any condition that renders the patient unable to understand instructions or safely interact with the GHOSTLY+ system THERAPISTS Inclusion Criteria: Therapists will be included if * They are licensed physiotherapists employed at one of the three participating clinical sites * They are involved in the daily rehabilitation of hospitalized older adults. Exclusion Criteria: Therapists will be excluded from participation if * They are unable or unwilling to complete the GHOSTLY+ training * They are not directly involved in the care of eligible patients during the study period * They express any conflict of interest or ethical concern that may compromise the integrity of the study
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What it tests

  • Gamified isometric strength training with blood flow restriction
  • Standard Physiotherapy
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Where

3 sites
Universitair Ziekenhuis Antwerpen
Antwerp, Belgium
Universitair Ziekenhuis Brussel
Brussels, Belgium
Universitair Ziekenhuis Leuven
Leuven, Belgium
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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