🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Personalized Music Therapy for Preterm Infants

RecruitingNAAges 5 Days - 15 DaysAllFabrizio Faina
NCT07295106 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Preterm infants in the Neonatal Intensive Care Unit (NICU) face environmental and clinical stressors that may affect physiological stability and development. This pilot randomized crossover study tests Personalized Music Therapy (PMT) based on recorded parental voices versus Quiet Rest. Outcomes include tissue oxygenation index (TOI) via near-infrared spectroscopy (NIRS) and heart rate (HR), respiratory rate (RR), and oxygen saturation (SpO2). Each infant completes two Periods (PMT and Quiet Rest) in randomized order, separated by a 2-day washout. Parental stress is measured at discharge using the Parental Stressor Scale: Neonatal Intensive Care Unit (PSS:NICU). Findings inform feasibility, variance estimates, and protocol refinements for a larger trial.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Preterm infants admitted to the Neonatal Intensive Care Unit (NICU) of Azienda Ospedaliera di Perugia, Santa Maria della Misericordia, Perugia (Italy) at the time of enrollment. * Gestational age at birth 28+0 to 36+6 weeks. * Age at enrollment: 5 to 15 days. * Stable vital signs at enrollment per unit policy. * Apgar score at 5 minutes ≥ 7. * Birth weight appropriate for gestational age, between the 50th and 90th percentile. * Written informed consent from parent(s) or legal guardian(s). Exclusion Criteria: * Post-operative status at the time of enrollment. * One or more of the following: intraventricular hemorrhage, necrotizing enterocolitis, sepsis, significant pulmonary disease, or neonatal anemia. * Congenital anomalies. * Hypersensitivity or intolerance to sound. * Maternal history of drug and/or alcohol misuse during pregnancy. * Lack of parental consent.
💊

What it tests

  • Personalized Music Therapy (PMT)
  • Quiet Rest
📍

Where

1 site
Neonatal Intensive Care Unit (NICU), Ospedale Santa Maria della Misericordia - Azienda Ospedaliera di Perugia
Perugia, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy