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โ† Trials
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Acute Effects of Cannabis on Cognition and Affect

RecruitingPhase 2Ages 21 Years - anyAllWashington State University
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In plain words

What the trial is, and whether it could suit you

This study will examine how a moderate dose of THC affects mood and cognitive functioning in regular cannabis users. The study uses a double-blind, placebo-controlled, crossover design, meaning each participant will complete two sessions. Specifically, each participant will be given active cannabis (20 mg THC) in one session, and placebo in the other session. The order will be randomized across participants, so half will receive cannabis first, and the other half will receive placebo first. Ninety two adults who use cannabis at least weekly will be recruited from the local community. After an online screening survey, eligible participants will attend a laboratory visit where the participants will provide informed consent and complete saliva and urine drug tests to confirm recent abstinence from cannabis and absence of other drugs. Participants who pass screening will complete baseline q

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * be 21 years of age or older * be fluent in English * use of cannabis at least once a week for at least one year * inhalation as their typical method of administration * be willing to abstain from cannabis on the day of their scheduled testing session Exclusion Criteria: * neurological conditions (e.g., neurodegenerative disorders, severe head injury, multiple concussions) * serious psychiatric conditions (e.g., psychosis, bipolar disorder) * family history of psychosis * intellectual disabilities or learning disorders (e.g., dyslexia) * chronic medical conditions that affect cognition or increase risk of cannabis use or exposure to cold water (e.g., heart disease, diabetes, peripheral neuropathy, history of fainting or seizures, fractures or wounds on both hands or wrists), * heart disease * BMI \> 34 * pregnant or lactating * use of illicit drugs in past 6 months * heavy use of alcohol (drinking \>4 drinks \>4 times per week) * nicotine/tobacco use * have experienced a severe adverse reaction to cannabis (e.g., panic attack, psychosis)
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What it tests

  • THC 20mg
  • Placebo
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Where

1 site
Washington State University
Pullman, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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