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โ† Trials
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VR Stimulation of Exercise Response in Sedentary Humans

RecruitingNAAges 25 Years - 40 YearsAllWayne State University
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In plain words

What the trial is, and whether it could suit you

Prolonged sedentary conditions contribute to declining health across human populations and cause significant secondary health consequences for many patients whose illnesses or injuries prevent them from exercising. The investigators have demonstrated that in a small animal fruit fly model, genetic stimulation of neurons that promote adrenergic signaling is sufficient to mimic the benefits of exercise training even in sedentary animals. The investigator's pilot work in humans has confirmed that humans respond to Virtual Reality (VR) stimuli that mimic exercise by increasing heart rate and altering heart rate variability in a way consistent with increased adrenergic activity. In this study, the investigators will directly test for the first time whether repeated, controlled exposure to VR stimuli that induce adrenergic activity in sedentary humans can produce adaptive changes to protein e

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Equal numbers male and female (32 each) 2. Blood glucose HbA1C: 5.7-6.4% or 100-125 mg/dL 3. BP: systolic\<120 and diastolic\<80 mmHg, systolic 120-129 mmHg and diastolic \<80 mmHg, or systolic \>130 mmHg and diastolic \>80 mmHg Exclusion Criteria: 1. BMI\>35kg/m2 2. Currently involved in an exercise program or similar activity 3. Taking medications that could affect results, including beta-blockers or SSRIs 4. Demonstrate any form of discomfort with the VR experience through self-reported feelings of anxiety or nausea 5. Alcohol consumption above a minimal level(\<2 oz/night) 6. BP: Systolic \>160 mmHg and Diastolic \>110 mmHg
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What it tests

  • 20 minutes cycling exercise
  • Virtual Reality
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Where

1 site
Wayne State University
Detroit, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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