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Mechanisms of Maternal Immune Tolerance in Early Pregnancy

Recruitingn/aAges 18 Years - anyFemaleUniversity Hospital, Basel, Switzerland
NCT07297394 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study explores the mechanisms of maternal immune tolerance in early pregnancy by characterizing immune cell profiles and functional pathways during the first trimester. The goal is to identify immunological factors that support healthy gestation and prevent complications such as miscarriages.

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📋 Eligibility rules (as published)
Inclusion Criteria: Blood from patients will be included before and during pregnancies (or failed implantation) conceived through IVF/ICSI (Intracytoplasmic Sperm Injection) treatment and in case of miscarriage. 1. where the patient (pregnant person) was ≥ 18 years of age. 2. where the patient (pregnant person) signed a written informed consent. Exclusion Criteria: 1. Certain maternal infections (HIV, Hepatitis B, Hepatitis C, Syphilis) 2. Patients under immunosuppressive medications (at time of blood sample collection)
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What it tests

  • Blood sampling
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Where

1 site
University Hospital Basel
Basel, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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