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Trial of Aldosterone-hybrid SteRoid for Guiding curablE Treatment of Primary Aldosteronism (TARGET-PA)

RecruitingNAAges 21 Years - anyAllChangi General Hospital
NCT07297745 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this project is to improve the diagnostic pathway for patients with primary aldosteronism, by validating non-invasive biomarkers coupled with routine computed tomography imaging. The aim is to reduce reliance on invasive procedures, shorten diagnostic timelines, and enhance accessibility to definitive diagnosis and treatment globally.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Confirmed diagnosis of primary aldosteronism according to the Endocrine Society guideline 2025. * Willing to undergo subtype testing with adrenal vein sampling and/or molecular imaging (Positron Emission Tomography/Computed Tomography, PET/CT). * Keen for surgical treatment if shown to have unilateral primary aldosteronism. Exclusion Criteria: * Inability to provide written informed consent.
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What it tests

  • Hybrid hormones
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Where

4 sites
Changi General Hospital
Singapore, Singapore
National University Hospital
Singapore, Singapore
Sengkang General Hospital
Singapore, Singapore
Singapore General Hospital
Singapore, Singapore
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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