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A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)

RecruitingPhase 1Ages 2 Months - 15 MonthsAllMerck Sharp & Dohme LLC
NCT07300267 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Researchers are looking for new vaccines to prevent pneumococcal disease, which is any infection in the lungs or other parts of the body that is caused by a type of bacteria called Streptococcus pneumoniae. V118C is a new vaccine designed to help prevent disease from Streptococcus pneumoniae bacteria. This study will look at V118C in toddlers and infants. The goal of the study is to learn how safe V118C is for children and how well they tolerate it.

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📋 Eligibility rules (as published)
Inclusion Criteria: The main inclusion criteria include but are not limited to the following: Stage 1: * Is previously vaccinated with 3 routine infant doses of Pneumococcal 20-valent conjugate vaccine (PCV20) * Is 12 through 15 months of age Stage 2: \- Is approximately 2 months of age Both Stages: * Was born at full term (gestational age greater than or equal to 37 weeks) Exclusion Criteria: The main exclusion criteria include but are not limited to the following: Stage 1: \- Has received a PCV dose at 10 months of age and older Stage 2: * Has received prior administration of any pneumococcal vaccine Both stages: * Has a history of invasive pneumococcal disease (IPD) * Has a known hypersensitivity to any component of V118C or PCV20 including diphtheria toxoid
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What it tests

  • V118C (Stage 1)
  • V118C (Stage 2)
  • PCV20 (Stage 1)
  • PCV20 (Stage 2)
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Where

15 sites
Madera Family Medical Group ( Site 1004)
Madera, United States
Acevedo Clinical Research Associates ( Site 1029)
Miami, United States
University of South Florida-Department of Pediatrics ( Site 1002)
Tampa, United States
Cotton O'Neil Research Center ( Site 1039)
Topeka, United States
University of Louisville, Norton Children's Research Institute ( Site 1005)
Louisville, United States
The Pediatric Center ( Site 1025)
Columbia, United States
Saint Louis University Center for Vaccine Development ( Site 1031)
St Louis, United States
Child Health Care Associates ( Site 1035)
East Syracuse, United States

…and 7 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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