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Effect of PRP Injection on Voice Recovery After Benign Vocal Fold Surgery

RecruitingNAAges 18 Years - 50 YearsAllBeni-Suef University
NCT07300800 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to evaluate whether platelet-rich plasma (PRP) injections can improve voice outcomes after microlaryngosurgery in patients with benign vocal fold lesions. The main questions it aims to answer are: Does postoperative PRP injection improve vocal quality compared to conventional surgery alone? Does PRP injection reduce vocal fatigue and improve patients' voice-related quality of life? Researchers will compare 32 patients receiving PRP injections after surgical removal of lesions (intraoperative injection) to 32 patients undergoing conventional surgery without PRP to see if PRP enhances recovery and voice function. Participants will: Undergo microlaryngosurgery to remove benign vocal fold lesions. Receive a PRP injection to the operated vocal fold and standard postoperative care. Or Standard postoperative care only. Complete voice assessments before

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๐Ÿ“‹ Eligibility rules (as published)
* Inclusion Criteria: \* Adults aged 18 to 50 years \* Diagnosis of a benign vocal fold lesion, including: Vocal fold polyps Vocal fold cysts Vocal fold nodules \* Failure to respond to conservative management, including one or more of the following: Voice rest, voice therapy * Exclusion Criteria: * Age younger than 18 years or above 50 * Medically unfit for surgery
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What it tests

  • Platelet-Rich Plasma (PRP) Injection after Microlaryngoscopic Surgery for PRP Group
  • Conventional Microlaryngoscopic Surgery (Active Comparator)
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Where

1 site
Beni Suef Univesity hospital
Banฤซ Suwayf, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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