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Cardiac Index-Guided Intraoperative Hemodynamic Management in Pediatric Moyamoya Surgery

RecruitingNAAges 1 Month - 18 YearsAllSeoul National University Hospital
NCT07304947 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective randomized controlled trial evaluates whether individualized cardiac index-guided intraoperative hemodynamic management reduces postoperative transient ischemic episodes in pediatric patients undergoing encephaloduroarteriosynangiosis (EDAS) for Moyamoya disease. Patients are randomized 1:1 to goal-directed fluid therapy based on baseline cardiac index versus standard arterial pressure-based management. The primary outcome is the incidence of transient ischemic episodes during hospitalization.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Pediatric patients \<18 years undergoing EDAS for Moyamoya disease under general anesthesia Exclusion Criteria: * ASA physical status 4-5 * Emergency surgery * Known cardiovascular disease * Any condition judged inappropriate by investigators
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What it tests

  • Cardiac Index-Guided Hemodynamic Management
  • Blood Pressure-Guided Standard Hemodynamic Management
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Where

1 site
Seoul National University Children's Hospital
Seoul, South Korea
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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