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โ† Trials
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A Prospective Longitudinal Observational Cohort Study of Pregnant Women Residing at High Altitude in Bolivia

Recruitingn/aAges 18 Years - 45 YearsFemaleMassachusetts General Hospital
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In plain words

What the trial is, and whether it could suit you

In this study, the investigators will follow two small cohorts of pregnant women: a cohort of healthy women with uncomplicated pregnancies residing at high altitude, a control group of healthy women with uncomplicated pregnancies residing at sea level, to characterize differences in cardiopulmonary adaptation and nitric oxide (NO) pathway expression at elevations \>3,500 m throughout pregnancy and into the postpartum period. The investigators aim to investigate right-sided cardiac impairment induced by chronic hypobaric hypoxemia, its effects on fetal growth, and the potential contribution of cardiovascular nitric oxide depletion to obstetric complications.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * women delivering at participating hospitals at more than 3500 meters or women delivering at participating hospitals at sea level * signed informed consent Exclusion Criteria: * preexisting cardiopulmonary pathologies (CHD, COPD, CKD, NYHA \> III)
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What it tests

  • Not listed
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Where

2 sites
Massachusetts General Hospital
Boston, United States
Hospital De La Meujer
La Paz, Bolivia
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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