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AI-Driven Dynamic Prediction of Non-Target Lesion Progression After PCI: A Chinese Multicenter Cohort Study

Recruitingn/aAges 18 Years - anyAllChina-Japan Friendship Hospital
NCT07312318 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Coronary artery disease remains a leading cause of global mortality. Although percutaneous coronary intervention (PCI) improves patient outcomes, the long-term risk of major adverse cardiovascular events (MACE) driven by the progression of non-target lesions (NTLs) remains substantial and continues to increase, while current risk stratification tools remain inadequate for predicting NTL progression. This multicenter cohort study aims to develop an artificial intelligence (AI)-driven system for the dynamic prediction and precision stratification of NTL progression after PCI. Utilizing comprehensive multimodal data from 52,577 Chinese patients-including clinical profiles, multi-omics blood biomarkers, and coronary imaging-the research pursues three primary objectives: (1) to identify and validate 2-3 specific biomarkers for NTL progression risk using multi-omics approaches; (2) to construc

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Aged 18 years or older; 2. Scheduled for or having undergone PCI; 3. Baseline plasma sample obtainable; 4. Informed consent obtained Exclusion Criteria: 1. Pregnancy or lactation; 2. Severe hepatic or renal dysfunction; 3. Active autoimmune disease; 4. Missing critical data
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What it tests

  • percutaneous coronary intervention
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Where

1 site
China-Japan Friendship Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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