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Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder

RecruitingPhase 4Ages 18 Years - 65 YearsAllUniversity of Sao Paulo General Hospital
NCT07313371 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a single-center, randomized intervention study in a volunteer population of patients with cocaine/crack use disorder to evaluate the pharmacological treatment of cocaine/crack craving, comparing the drug clonidine with the active placebo clonazepam.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients hospitalized in the adult Alcohol and Drugs ward of the Perdizes Institute (IPer) at the Hospital das Clínicas, University of São Paulo Medical School * DSM-5 criteria for cocaine and/or crack use disorder * Voluntarily seeking treatment * Must be able to swallow pills Exclusion Criteria: * Inability to read and/or understand the study questionnaires * benzodiazepine use disorder * opioid use disorder * alcohol use disorder
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What it tests

  • clonidine
  • clonazepam 0,25 mg
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Where

1 site
Instituto Perdizes
São Paulo, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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