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Repetitive Transcranial Magnetic Stimulation in Frontotemporal Lobar Degeneration

RecruitingNAAges 18 Years - anyAllUniversitร  degli Studi di Brescia
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In plain words

What the trial is, and whether it could suit you

The aim of the study is to evaluate the safety, feasibility, clinical and biological efficacy, and predictors of efficacy of an intervention consisting of repetitive transcranial magnetic stimulation (rTMS) in patients with frontotemporal dementia (FTLD) or in asymptomatic persons at risk of FTLD (i.e., persons familiar with FTLD patients). rTMS is a non-invasive brain stimulation technique, and has demonstrated the ability to modulate neuronal activity by applying high-frequency magnetic fields to the surface of the skull. rTMS offers a potentially effective means to influence neural networks involved in the pathogenesis of neurodegenerative diseases, with benefits that could extend beyond symptomatic relief. Its safety has been widely documented in a variety of clinical conditions, making it an ideal candidate for application in neurodegenerative diseases. In the present study, parti

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * diagnosis of FTLD (bvFTD, avPPA, svPPA, CBS, or PSP) * global CDR plus NACC FTLD โ‰ค 1 Exclusion Criteria: * presence of cerebrovascular disease, hydrocephalus, intracranial masses identified by MRI, history of head trauma, serious medical conditions unrelated to FTLD, history of epilepsy, and presence of electronic (e.g., pacemaker) or metallic implants in the head.
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What it tests

  • Theta burst stimulation
  • Sham Theta burst stimulation
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Where

1 site
IRCCS Istituto Centro San Giovanni Di Dio - Fatebenefratelli Brescia
Brescia, Italy
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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