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Pain in Pediatric Patients - Internet Interventions for Disorders of Gut-brain Interaction

RecruitingNAAges 8 Years - 17 YearsAllKarolinska Institutet
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In plain words

What the trial is, and whether it could suit you

Many children and adolescents often experience long-lasting stomach pain. In many cases, this is due to disorders of gut-brain interaction (DGBI), such as irritable bowel syndrome (IBS), functional abdominal pain, and functional dyspepsia. These conditions are caused by disrupted communication between the brain and the gut. They are linked to significant suffering, reduced quality of life, and higher school absenteeism. Psychological treatments such as cognitive behavioral therapy (CBT) have shown good effect, but waiting times within healthcare are often long. Therefore, there is a need for more accessible and cost-effective treatment alternatives. The goal of this clinical trial is to explore whether gut-directed hypnotherapy, already used successfully in the Netherlands, can be implemented as a new treatment option in Swedish healthcare. In addition, the study will compare gut-direct

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age 8-17 years * Basic somatic work-up completed (CRP/ESR, TGA, complete blood count, fecal calprotectin) * Confirmed DGBI diagnosis: IBS, functional abdominal pain, or functional dyspepsia (according to Rome IV criteria) * Any constipation must be treated according to current clinical guidelines, with stable laxative dosing for at least one month prior to referral * In cases of celiac disease, the participant must have followed a gluten-free diet for at least six months and TGA values must have normalized * For participants with a neuropsychiatric diagnosis treated with medication, at least two months must have passed since the last dose adjustment * At least one parent and the child/adolescent must be fluent in Swedish and willing to participate in both the educational program and treatment (regardless of randomization outcome), complete homework assignments, and respond to questionnaires Exclusion Criteria: * Other organic disease that better explains the gastrointestinal symptoms * At referral assessment, psychiatric symptoms or psychosocial problems - such as severe bullying, high school absenteeism, or difficult family circumstances - are judged to be more prominent than the gastrointestinal problems and require more extensive, multiprofessional care than what the study can offer * Participants who have already completed gut-directed hypnotherapy or CBT
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What it tests

  • Gut-directed hypnotherapy
  • Cognitive-behavioral therapy
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Where

1 site
Sachs Children's Hospital
Stockholm, Sweden
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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