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The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis

RecruitingNAAges 18 Years - 75 YearsAllSaglik Bilimleri Universitesi
NCT07320846 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to examine the effects of traditional respiratory rehabilitation and respiratory muscle strengthening training added to this program at the genetic level in in patients with rheumatoid arthritis-associated interstitial lung disease. The main questions it aims to answer are: * Does respiratory muscle strengthening exercise added to respiratory rehabilitation in patients with rheumatoid arthritis-associated interstitial lung disease have additional benefits on rehabilitation outcome measures such as exercise capacity, shortness of breath, and muscle strength? * Does the gain obtained with respiratory muscle strengthening iin patients with rheumatoid arthritis-associated interstitial lung disease increase the quality of life of patients and have a positive effect on their psychological state? * Does respiratory rehabilitation applied to iin patients

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosed with RA according to the ACR/EULAR 2010 classification criteria * Duration of diagnosis greater than 2 years * Disease activity with a DAS28 score below 5.1 * Voluntary participation in the study * Presence of lung involvement Exclusion Criteria: * Having orthopedic deformities that may affect the treatment program * Pregnancy * Uncontrolled diabetes or heart disease * Participation in a rehabilitation program within the last 6 months * Body Mass Index (BMI) \> 30 * Patients with severe organ failure * Recent acute coronary syndrome * Presence of active infection
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What it tests

  • Standard pulmonary rehabilitation programme
  • Resistive threshold inspiratory muscle training
  • No intervention
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Where

1 site
University of Health Sciences
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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