AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Patient-specific Reconstruction Plate for Segmental Mandibular Defects

RecruitingNAAges any - anyAllAlexandria University
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

The mandible's horseshoe-shaped anatomy makes the reconstruction of segmental defects a challenging procedure. Conventional reconstruction typically relies on alloplastic plates to bridge bony stumps; however, these require extensive intraoperative bending, often resulting in imperfect adaptation, press-to-contact fixation, and residual stresses that increase the risk of hardware fatigue and fracture. Recent advances in computer-aided design and manufacturing (CAD/CAM) and virtual surgical planning (VSP) have improved precision in maxillofacial reconstruction. Patient-Specific Reconstruction Plates (PSRP), developed from virtual planning and patient-specific anatomical data, offer a bespoke contour adaptation, predictable screw positioning, and elimination of press-fit deformation. This customization improves alignment, mechanical stability, and long-term outcomes.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Patients with a segmental mandibular continuity defect, not involving the condyle. 2. Patients suffering from benign, locally invasive or malignant lesions that involving the lower border of the mandible. 3. Patients with recurrent lesions after resection. 4. Patients dealing with osteomyelitis or jaw osteonecrosis that is indicated for sequestrectomy. โ€ข Stage-III jaw osteonecrosis. 5. Patients with traumatic defects. 6. Patients with post-gunshot mandibular defects. Exclusion Criteria: 1. Medically compromised patients contradict the operation. 2. Patients with segmental mandibular defects that require condylar process resection 3. Patients with lateral segmental mandibular defects involving the condyle that require reconstruction using an alloplastic total joint. 4. Patients with an active infection at the site of resection.
๐Ÿ’Š

What it tests

  • Patient specific reconstruction plate
๐Ÿ“

Where

1 site
Faculty of Dentistry, Alexandria University
Alexandria, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy