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Effect of Tegileridine Versus Sufentanil as Analgesic Components on Opioid-Induced Cough During Anesthesia Induction

RecruitingNAAges 18 Years - 65 YearsAllThe First People's Hospital of Lianyungang
NCT07323043 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In patients undergoing general anesthesia with planned tracheal intubation , a prospective, randomized, controlled study was conducted to record the occurrence of cough 2 minutes after injection of Sufentanil or Tegilerdine. The cough was graded based on the frequency and duration: Grade I, no cough; Grade II, a single mild cough; Grade III, multiple coughs with duration \<1 second; Grade IV, continuous coughing with a duration \>15 seconds.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age between 18 and 65 years, 18 ≤ BMI (kg/m²) ≤ 30; 2. ASA grade I \~ III; 3. Scheduled elective surgery under general anesthesia with tracheal intubation. Exclusion Criteria: 1. Patients with chronic cough (cough lasting \>8 weeks) or asthma; 2. Patients with a history of allergy to the drugs used during the study; 3. Patients with severe cardiovascular disease, intracranial lesions, eye lesions, or lung lesions.
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What it tests

  • Tegilerdine
  • Sufentanil
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Where

1 site
The Affiliated Lianyungang Hospital of Xuzhou Medical University
Lianyungang, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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