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Single- vs Double-Layer Cesarean Scar Repair and Myometrial Thickness

RecruitingNAAges 18 Years - 44 YearsFemaleAnkara City Hospital Bilkent
NCT07323355 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Cesarean delivery (CD) is one of the most commonly performed surgical procedures worldwide, with a rising incidence particularly in high-income countries. Although often life-saving, cesarean delivery carries both short- and long-term maternal risks. Early complications include infection, hemorrhage, and thromboembolism, while inadequate uterine healing can lead to future complications such as uterine rupture and placenta accreta spectrum disorders. Additionally, cesarean scars may result in pregnancy complications, isthmocele formation, postmenstrual bleeding, pelvic pain, and dysmenorrhea. This highlights the need for optimization of the surgical technique. Despite increasing cesarean rates, there is no consensus on the optimal uterine closure method. Techniques vary in terms of the number of layers, suture locking style, and inclusion of the endometrium, and their comparative effectiv

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📋 Eligibility rules (as published)
Inclusion Criteria: * Female participants aged 18-44 years. * Undergoing cesarean delivery at the study hospital's Obstetrics and Gynecology clinic. * Evaluated as clinically eligible based on history, physical examination, abdominal ultrasonography, and routine preoperative laboratory tests, including: Complete blood count (CBC), biochemical profile, prothrombin time (PT), activated partial thromboplastin time (aPTT), blood group determination. No abnormalities detected in the above assessments. Exclusion Criteria: \- Presence of chronic diseases, including: Rheumatologic diseases, renal failure, vascular malformations, hypertension, cardiac disease, diabetes mellitus, obesity, thyroid disease, congenital hematologic disorders. * Suspected or confirmed placenta previa or placenta accreta spectrum. * Clinical chorioamnionitis. * Anterior wall uterine myomas. * History of low transverse nonstandard uterine incision. * Predicted obstetric hemorrhage or other intraoperative complications.
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What it tests

  • Double-Layer Cesarean Scar Repair
  • Single-Layer Cesarean Scar Repair
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Where

1 site
Ankara Bilkent City Hospital
Ankara, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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