🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2026 and 2029.

Recruitingn/aAges 18 Years - anyAllBernardino Clavo, MD, PhD
NCT07325851 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The main objective of this study is to analyze the impact on the health-related quality of life of patients with refractory symptoms who have been referred to the Dr. Negrín University Hospital Chronic Pain Unit for adjuvant palliative treatment with ozone therapy between January 2026 and December 2029. Additionally, the study aims to evaluate several specific symptoms, hyperspectral and thermal images, non-invasive clinical parameters related to the Autonomic Nervous System (such as heart rate variability, electrochemical skin conductance, and vibration perception thresholds), oxidative stress and inflammatory parameters, and gut microbiota composition.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * 1\. Adults ≥ 18 years old. * 2\. Patients referred to the Chronic Pain Unit of the Dr. Negrín University Hospital for symptomatic/palliative treatment with ozone therapy because conventional treatment does not exist, has failed, has offered insufficient results, or is associated with high risk/morbidity. * 3\. After evaluation of symptoms and patients, it exists a potential benefit of adding ozone treatment to the current treatment. * 4\. Patients have no contraindications for ozone treatment. * 5\. Patients must sign the specific Informed Consent for this study and for the ozone treatment. Exclusion Criteria: * 1\. Age \< 18 years old. * 2\. Psychiatric illness or social situations that would limit compliance with study requirements. Contraindication or disability to attend scheduled treatments. * 3\. Contraindication or disability to attend scheduled treatments. * 4\. Uncontrolled clinical conditions (e.g., severe heart failure, massive hemorrhage, status epilepticus). * 5\. Life expectancy \< 6 months. * 6\. Known allergy to ozone. * 7\. Hemochromatosis (for systemic ozone treatment). * 8\. Pregnancy (for systemic ozone treatment). * 9\. Significant Glucose-6-Phosphate Dehydrogenase deficiency (Favism) (for systemic ozone treatment). * 10\. Patients who do not meet the inclusion criteria.
💊

What it tests

  • Ozone Therapy
📍

Where

1 site
Dr. Negrín University Hospital
Las Palmas de Gran Canaria, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy