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The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel.

RecruitingNAAges 18 Years - anyAllKing Abdullah University Hospital
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel. The main questions it aims to answer are: * Does NBF gel enhance wound healing after graft harvesting from the palate? * Does NBF gel reduce the number of inflammatory mediators after surgery? * Does NBF gel reduce pain and discomfort at the palatal donor site? Researchers will compare NBF gel to a placebo (a look-alike gel that does not contain the active ingredients) to see if NBF gel enhances wound healing. Study steps include: * Participants will apply the assigned gel on the surgical wound 4 times a day for 4 weeks. * Clinical photographs and measurements will be obtained on days (0, 1, 2, 4, 7, 15, 21, 30). * Wound fluid samples will be collected on days (0, 1, 2, 4, 7). * Partic

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Patients with gingival recession that is indicated for root coverage or need for phenotype modification. 2. 18 years or older. 3. absence of systemic disease 4. Non-smoker 5. No use of antibiotics, corticosteroids, anti-inflammatory medication or hormones in the past 3 months Exclusion Criteria: 1. Pregnant or lactating woman. 2. patients with immune or systemic diseases. 3. Patients with an allergy to any ingredient in the gel.
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What it tests

  • Application of NBF gel after soft tissue graft surgery
  • Application of placebo gel after soft tissue graft surgery
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Where

1 site
Jordan University of Science and Technology, Faculty of Dentistry
Irbid, Jordan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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