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Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologies

Recruitingn/aAges 18 Years - 60 YearsAllSpitalul Clinic de Boli Infecțioase și tropicale …
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In plain words

What the trial is, and whether it could suit you

Timely detection of signs of raised intracranial pressure or persistent inflammation within the meninges can expedite therapeutic decisions improving the prognosis of patients with brain damage. Optic nerve ultrasonography provides a user-friendly, safe, low-cost, and non-invasive imaging method that can be easily deployed for ICU patient assessment. This study aims to evaluate the sensitivity and specificity of optic nerve ultrasound in estimating cerebral inflammation extension and cerebral edema in patients in the ICU. The working hypothesis is that optic nerve ultrasound is a useful tool in the rapid diagnosis of cerebral edema and the presence or persistence of cerebral inflammation, which can enable adapted and rapid therapeutic interventions.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Patients admitted into one of the specified wards of the involved hospitals * Patients aged 18-60 years * Suspected meningitis, encephalitis, stroke or cerebral tumors Exclusion Criteria: * Age under 18 years or over 60 years old * Ocular lesions preventing ocular ultrasound (palpebral infections, cornean erosions, glaucoma, trauma) * Conditions preventing lumbar puncture (coagulation disorders, epidural abscesses, local infections)
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What it tests

  • Optic Nerve Sheath Diameter
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Where

2 sites
Fundeni Clinical Institute
Bucharest, Romania
"Dr. Victor Babeș" Clinical Hospital for Infectious and Tropical Diseases
Bucharest, Romania
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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