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HELO Trial: Energy-Based Therapies vs. Conventional Hemorrhoidectomy for Grade III Hemorrhoids

RecruitingNAAges 18 Years - 75 YearsAllChang Gung Memorial Hospital
NCT07333040 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective, multicenter study compares the efficacy and functional outcomes of three surgical treatments for symptomatic Goligher Grade III internal hemorrhoids: Laser Hemorrhoidoplasty (LHP), Hemorrhoid Energy Therapy (HET), and conventional closed hemorrhoidectomy (Ferguson technique). Due to strong patient preferences in hemorrhoidal surgery, this study utilizes a pragmatic, preference-tolerant design. Eligible patients will undergo standardized counseling and select their preferred treatment arm. The study aims to evaluate whether minimally invasive energy-based therapies offer superior postoperative pain relief and faster functional recovery compared to conventional hemorrhoidectomy

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosed with Goligher Grade III internal hemorrhoids. * Symptomatic with HDSS score \>= 5. * Age 18-75 years. * Fit for general anesthesia or sedation. * Able to provide informed consent. * Agree to pre-operative photo documentation. Exclusion Criteria: * Other anorectal diseases (fistula, abscess, IBD, malignancy). * Prior anorectal surgery within 6 months. * Pregnancy or lactation. * Contraindications to anesthesia.
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What it tests

  • Laser Hemorrhoidoplasty (LHP)
  • Hemorrhoid Energy Therapy (HET)
  • Ferguson Hemorrhoidectomy
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Where

1 site
Chang Gung Memorial Hospital, Linkou Branch
Taoyuan, Taiwan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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