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TROPIS Versus Coring Out Fistulectomy in High Anal Fistula

RecruitingNAAges 18 Years - anyAllCairo University
NCT07334678 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

High anal fistulas represent a surgical challenge due to high recurrence rates and risk of postoperative fecal incontinence. Several sphincter-preserving techniques have been developed to address these issues. Coring Out fistulectomy is a traditional sphincter-saving approach, while Transanal Opening of the Intersphincteric Space (TROPIS) is a recently introduced technique with promising outcomes. This randomized clinical trial aims to compare the efficacy, safety, and patient outcomes of TROPIS versus coring out fistulectomy in the management of high complex anal fistulas.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with high anal fistula ( involving more than 1/3 of the sphincter complex), whether de novo or recurrent Exclusion Criteria: * Patients with fistula secondary to malignancy, inflammatory bowel disease, trauma or radiation * Patients with Low anal fistula * Patient with preoperative fecal incontinence * Previous levator ani muscle injury
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What it tests

  • Transanal opening of intersphincteric space (TROPIS)
  • Coring Out Fistulectomy
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Where

1 site
Faculty of medicine Cairo University
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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