💬In plain words
What the trial is, and whether it could suit you
The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate effects on sensorimotor and cognitive functions after neurological injuries affecting the upper limb (cervical spinal cord injury and stroke). Secondary objectives are to evaluate the relevance of anatomical MRI, functional MRI, and neurophysiological measurements for optimizing and predicting the effects of these different interventions.
Sign in to get the eligibility rules as simple questions to take to your doctor.
📋 Eligibility rules (as published)
Inclusion Criteria:
CONTROL GROUP:
* Over 18 years of age
* Participant who has signed an informed consent form
* Participant who is affiliated with and covered by the social security system
POST-STROKE GROUP:
* Over 18 years of age
* Who sustained a stroke more than 3 weeks ago
* Considered medically stable by the medical investigator
* Who has signed an informed consent form
* Affiliated with and covered by the social security system
SCI GROUP:
* Over 18 years of age
* Considered to have a complete or incomplete spinal cord injury (i.e., with a score on the Spinal Injury Association (ASIA) Impairment Scale (AIS) score from A to D)
* Considered medically stable by the investigating physician
* Presenting with quadriplegia due to cervical injury
* Who has signed an informed consent form
* Affiliated with and covered by the social security system.
Exclusion Criteria:
* Suffering from a chronic condition
* Skin problems or open wounds
* History of epilepsy or seizures
* Presence of a contraindication to the use of magnetic/electrical stimulation or MRI, including: cardiac pacemaker; implanted hearing aid; intraocular foreign body, shrapnel, or bullets; metal worker; pacemaker or neurostimulator; claustrophobia
* Presence of implanted medical devices (cardiac valve, endovascular devices, ventricular shunt valve, surgical clips, metallic sutures, staples, stent, osteosynthesis or arthrodesis hardware) not classified as "MR Conditional" according to ASTM F2503.
* Individuals who are legally incompetent, under judicial protection, guardianship, or trusteeship
* Pregnant and/or breastfeeding women
* Individuals who refuse to be informed of any abnormalities that may be detected by MRI.
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