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Eye Imaging for the Study of Childhood Myopia

RecruitingNAAges 6 Years - 12 YearsAllEssilor International
NCT07335146 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Myopia (nearsightedness) is increasing worldwide and is becoming a serious public health problem. Studies estimate that by 2050, if no action is taken, almost half of the world's population will be myopic. About 10% of people could develop severe myopia, which increases the risk of serious eye problems such as retinal detachment, damage to the macula, or glaucoma. Children are particularly affected because myopia often worsens as they grow. Several treatments are now available to slow the progression of myopia in children, but these treatments are not equally effective for everyone. Some children respond better than others, and the reasons for these differences are not yet well understood. One possible explanation is that differences in eye anatomy may influence the effectiveness of a treatment. This suggests that myopia treatments may need to be tailored to each child. By studying the

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📋 Eligibility rules (as published)
Inclusion Criteria: * Spherical equivalent under cycloplegia greater -9.75 D and less than 2 D * Beneficiary of social security * Written consent from both holders of parental authority (or from one in case of exclusive parental authority) Exclusion Criteria: * Declared neurological deficit, including history of epileptic pathology or sensory-motor coordination disorders, vestibular or cerebellar pathology (for example, balance disorders) * Current or progressive pathology of the eyes or their appendages that may affect vision, other than myopia (examples: glaucoma, retinitis pigmentosa…) * Declared aphakia or pseudophakia (intraocular implant) * Ocular motility problem such as strabismus or nystagmus * Contraindication to MRI (claustrophobia, implanted devices such as pacemaker, etc.) * Wearing fixed orthodontic appliances that affect the quality of orbital MRI scans
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What it tests

  • Ophtalmic measurements to estimate geometrical distances
  • MRI
  • Ophtalmic measurements to measure wavefront aberrations
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Where

1 site
Hôpital Fondation Adolphe de Rothschild
Paris, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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