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Single Dose Preemptive Paracetamol or Ibuprofen Before Septrorhinoplasty on Intra- and Postoperative Opioid Consumption.

Recruitingn/aAges 18 Years - anyAllSamsun University
NCT07337629 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Reducing intra- and postoperative pain or using less opioids is an essential strategy in today's operations. One emerging and widely used method in this context is the use of preemptive analgesic medication. Paracetamol and ibuprofen used preemptively have been shown to reduce postoperative opioid use and pain scores. There are also studies showing that preemptive analgesia with different analgesic medications reduces opioid consumption and postoperative pain. Our study will evaluate both the intraoperative and postoperative effectiveness of paracetamol and ibupurofen with preemptive analgesia, considering total opioid use. It will also investigate drug side effects and their advantages using a 15-question compilation quality scale, validated in Turkish.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Septorhinoplasty surgery * ASA1-2 patients * Men and women aged 18-65 * Informed consent and acceptance to participate in the study Exclusion Criteria: * ASA 3-4 and under 18 years of age * Patients with serious renal, hepatological, cardiovascular, or pulmonary system diseases * Allergy to paracetamol or ibuprofen * Patients with bleeding diathesis, platelet dysfunction, GI disease, peptic ulcers, pregnancy, planning pregnancy, and breastfeeding mothers * Patients using ASA or anticoagulants
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What it tests

  • Not listed
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Where

1 site
Samsun University Samsun Training and Research Hospital
Samsun, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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