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Chest Wall Reconstruction Cohort

RecruitingNAAges 18 Years - anyAllUniversity of Health Sciences Lahore
NCT07338006 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Chest wall reconstruction following tumor or infection-related resections remains a challenging aspect of thoracic surgery, requiring restoration of structural stability and preservation of respiratory mechanics. While polymethyl methacrylate (PMMA) bone cement has long been used for rigid reconstruction, its limitations-including high cost, rigidity, infection risk, and interference with normal respiratory motion-pose challenges in resource-constrained settings. Twisted stainless steel wires offer a low-cost, flexible alternative that allows dynamic chest wall movement and easier adaptability in low- and middle-income countries such as Pakistan. To compare postoperative outcomes, complications, and cost-effectiveness of chest wall reconstruction using twisted stainless steel wires versus PMMA bone cement over a two-year period (January 2025 - December 2026). This prospective cohort st

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged ≥18 years undergoing partial or full-thickness chest wall resection. * Defects requiring rigid or semi-rigid reconstruction involving two or more ribs or the sternum. Exclusion Criteria: * Patients with small defects managed by primary closure or soft tissue-only reconstruction. * Patients with concurrent major intrathoracic resections (e.g., pneumonectomy) may confound postoperative respiratory assessment. * Recurrent disease requiring revision reconstruction. * Patients unwilling or unable to provide consent or comply with follow-up.
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What it tests

  • chest wall reconstruction
  • Chest wall reconstruction
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Where

1 site
Services Hospital, Lahore
Lahore, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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