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โ† Trials
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Steroid Use in Treatment of Allergic Reactions to Food

RecruitingPhase 4Ages 6 Months - 18 YearsAllJohannes Trueck
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In plain words

What the trial is, and whether it could suit you

In this study, the investigators want to find out whether a specific medication commonly used for severe allergic reactions is really necessary. When children have allergic reactions to foods, they are often given medications to relieve the symptoms. In addition to adrenaline and antihistamines, steroids are frequently administered in German-speaking Switzerland. However, it is unclear whether steroids are really helpful in this situation. To investigate this, the investigators are comparing two groups: one group receives additional steroids, and the other does not. Which treatment a participant receives is decided randomly, like flipping a coin. The study takes place during a pre-scheduled provocation test at the clinic. If an allergic reaction occurs, the usual emergency medications will be administered. Doctors will closely monitor how the reaction develops. No additional tests or vis

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * suspected or confirmed IgE-mediated food allergy Exclusion Criteria: * Non-IgE mediated food allergies * Non-food allergies * Age outside the specified range * Contraindications for an oral food challenge or oral steroid use within one week before the challenge.
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What it tests

  • Antihistamines
  • Systemic corticosteroids
  • Adrenaline (rescue medication)
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Where

2 sites
University Children's Hospital Basel
Basel, Switzerland
University Children's Hospital, Zรผrich
Zurich, Switzerland
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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