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Dual-energy CT vs. MRI in the Evaluation of Squamous Cell Carcinomas of the Oral Cavity and Oropharynx

Recruitingn/aAges 18 Years - anyAllUniversity Hospital, Strasbourg, France
NCT07343271 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The diagnostic and pre-therapeutic assessment of squamous cell carcinomas requires a neck and chest CT scan and a neck and facial MRI, which is the most effective examination, to establish the TNM stage of the tumor. However, obtaining this complete assessment can delay treatment. Confirmation of the non-inferiority of 40keV dual-energy CT in BOLT compared to MRI would spare the patient an additional MRI examination, speed up the pre-treatment assessment, reduce the loss of opportunity due to delayed treatment, and free up MRI imaging slots, which are still insufficient in the region.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patient (≥18 years) * presenting with oral or oropharyngeal squamous cell carcinoma proven by histopathological analysis of a biopsy * having undergone a clinical examination with nasofibroscopy by an ENT surgeon specializing in cancer surgery * a contrast-enhanced cervicofacial MRI * and a contrast-enhanced cervicofacial DECT with BOLT maneuver. Exclusion Criteria: * A lesion other than oral or oropharyngeal squamous cell carcinoma * A labial location * A contraindication to performing one or both of the imaging examinations.
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What it tests

  • Not listed
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Where

1 site
Service d'ORL et de Chirurgie Cervico-faciale - CHU de Strasbourg - France
Strasbourg, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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