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Congestion and LActate at diScHarge in Acute Heart Failure

Recruitingn/aAges 18 Years - anyAllUniversity of Monastir
NCT07345156 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Acute heart failure (AHF) is a leading cause of hospitalization and is associated with high short-term morbidity and mortality, with 20-30% of patients experiencing rehospitalization or death within 30 days. Early adverse events often reflect incomplete recovery, highlighting the need for improved risk stratification after clinical stabilization .Current prognostic approaches mainly focus on hemodynamic congestion. Persistent pulmonary congestion at discharge is a strong predictor of poor outcomes, but these markers primarily assess macrocirculatory abnormalities and do not capture microcirculatory dysfunction, which may persist despite apparent clinical improvement. Lung ultrasound, through the Lung Ultrasound Score (LUS), provides a validated assessment of pulmonary congestion and has demonstrated prognostic value in AHF. However, LUS does not reflect systemic tissue perfusion. In cont

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years. * Hospitalization for acute heart failure/decompensation (clinical diagnosis + imaging/laboratory tests according to local practice). * Patient deemed ready for discharge (decision made by the team, discharge within 24 hours). Exclusion Criteria: * Septic shock/severe active infection at the time of discharge. * Hypoxemia or respiratory distress requiring high-flow oxygen/ventilation at the scheduled time of discharge. * Severe cirrhosis/advanced liver failure. * Refusal to participate. * Technical impossibility of LUS.
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What it tests

  • Lung Ultrasound Score
  • Lactate Blood Test
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Where

1 site
Fattouma Bourguiba Hospital of Monastir
Monastir, Tunisia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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