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Clinical Study on the Safety and Efficacy of Temporal Interference Stimulation in the Treatment of Post-Stroke Aphasia

RecruitingNAAges 18 Years - 80 YearsAllThe First Affiliated Hospital of Anhui Medical Un…
NCT07346378 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Neurological disorders encompass a wide variety of diseases, including congenital and neurodevelopmental disorders, cerebrovascular and neurodegenerative diseases, nervous system infections, neuroimmune diseases, neuromuscular or peripheral nervous system disorders, traumatic injuries, and tumor-related neurological conditions, with diverse symptomatic manifestations. The etiology, symptoms, and disease courses of these disorders vary significantly, severely impacting human health and social development, and have become a critical global public health issue. Some neurological disorders can lead to lifelong disability or high mortality rates, while others remain poorly understood, lacking effective treatments or cures. Post-stroke aphasia (PSA) is an acquired language impairment caused by ischemic or hemorrhagic injuries to the central nervous system. Its clinical manifestations are dive

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosed with post-stroke aphasia; * Right-handed; * Native Chinese speaker with comprehension of Mandarin; * Aged 18-80 years; * Complete relevant assessment and imaging data; * Informed consent obtained from the patient and their family. Exclusion Criteria: * Cerebellar involvement in the stroke lesion, and incomplete scanning of cerebellar structures; * Severe dysarthria; * Concurrent epilepsy with occasional seizures; * Implanted pacemaker or deep brain stimulator; * History of brain tissue resection for prior lesions such as brain tumours or brain abscesses; * Other severe psychiatric disorders.
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What it tests

  • temporal interference stimulation
  • speech and language therapy
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Where

1 site
The First Affiliated Hospital of Anhui Medical University
Hefei, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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